Pollutant dispersion modelling is instrumental in assessing the dispersion of hazardous fumes emitted from laboratory or industrial exhaust plumes. Considering the criticality of the laboratory applications, emission of hazardous fumes from laboratory/Industrial exhaust plume. Industrial exhaust plumes also release pollutants into the atmosphere, including gases, particulate matter, and volatile organic compounds. Understanding the dispersion patterns of these pollutants is essential for evaluating the impact on air quality, human health, and the surrounding ecosystem. Pollutant dispersion modelling in any environment involves the use of Computational Fluid Dynamics (CFD) techniques. CFD simulations consider factors such as exhaust velocity, stack height, atmospheric conditions, and surrounding terrain to predict the dispersion and concentration of pollutants. These Tools also helps to analyse and investigate dilution of pollutant airs and their movement around and in the vicinity of the building for critical wind conditions typical for the site and assess the level of re-entrainment of the building’s exhausts, if any, at the building’s fresh air intakes.